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pentobarbital will reduce the level or result of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic influence of elbasvir/grazoprevir could be minimized if coadministered with sturdy CYP3A inducers which is thus contraindicated.pentobarbital will lessen the extent or result of aprepitan